LOXONIN TABLETS 60mg 镇痛/抗炎/退烧药 洛索洛芬钠片 [0114987081105400]

LOXONIN TABLETS 60mg 镇痛/抗炎/退烧药 洛索洛芬钠片 [0114987081105400]

Price: US$23.00(tax included)

List Price: US$27.60

Weight: 60g

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Item description

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
LOXONIN TABLETS 60mg
 Active ingredient:
Loxoprofen sodium hydrate
 Dosage form:
faintly reddish tablet, diameter: 9.1mm, thickness: 3.3mm
 Print on wrapping:
ロキソニン 60mg, 157, Loxonin 60mg, 鎮痛・抗炎症・解熱剤

Effects of this medicine

This medicine suppresses prostaglandin synthesis that causes inflammation, and acts to ease swelling/pain induced by inflammation as well as to bring down fever.
It is usually used to treat rheumatoid arthritis and osteoarthritis. It is also used to reduce pain and inflammation after surgery, wounds and tooth removal, as well as to bring down fever or ease pain induced by acute inflammation of upper respiratory tract.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: peptic ulcer, blood disease, liver/kidney/heart disorders, aspirin asthma or its history.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For the use in reducing inflammation and pain induced by rheumatoid arthritis, osteoarthritis, lumbar pain, frozen shoulder, neck-shoulder-arm syndrome, tooth pain, as well as after surgery/wounds/tooth removal: In general, for adults, take 1 tablet (60 mg of loxoprofen sodium) at a time, 3 times a day. If taken as on-demand use, take 1 to 2 tablets (60 to 120 mg) at a time.
    For the use in reducing fever or pain induced by acute inflammation of upper respiratory tract
    : In general, for adults, take 1 tablet (60 mg of loxoprofen sodium) at a time, as needed. Usually up to twice a day. Do not exceed 3 tablets (180 mg) a day.
    The dose may be adjusted according to your age and symptoms. Avoid taking the medicine on an empty stomach. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include gastric discomfort, pain in the pit of the stomach, stomachache, nausea/vomiting, loss of appetite, edema/swelling, rash, hives, drowsiness, fever, and itch. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • pale face, breathing difficulty, cold sweat [shock, anaphylaxis]
  • nose/gums bleeding, bruising on the limbs [agranulocytosis, hemolytic anemia, leukopenia, thrombocytopenia]
  • redness/swelling/rash/blister of skin/mucous membrane, fever, general malaise [toxic epidermal necrosis, oculomucocutaneous syndrome]
  • decreased urine output, swelling, loss of appetite [acute renal disorder, nephrotic syndrome, interstitial nephritis]
  • breathing difficulty, general swelling [congestive heart failure]
  • fever, cough, breathing difficulty [interstitial pneumonia]
  • blood vomiting, blood in stool [digestive tract bleeding]
  • pain in the pit of the stomach, stomachache [digestive tract perforation]
  • nausea, stomachache, abdominal enlarged feeling [constriction and obstruction of the intestinal tract]
  • general fatigue, nausea, yellowing of the skin/white of eyes [liver dysfunction, jaundice]
  • breathlessness, wheezing [asthma attack]
  • fever, headache, nausea [aseptic meningitis]
  • sore muscle, feeling of weakness [rhabdomyolysis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

简介:

商品名称:LOXONIN TABLETS
英文名称:Loxoprofen Sodium Hydrate
中文名称:洛索洛芬钠片
生产厂家:第一三共制药
ロキソニン錠60mg/ロキソニン細粒10%


药效分类
镇痛、抗炎、退烧药
批准日期:2009年9月
商標名
LOXONIN TABLETS

 

 

药效药理
聚氯乙烯水和物具有良好的镇痛、抗炎症、解热作用,但是特别是镇痛作用非常强。本药剂还会起到专业药物的作用,它会在从消化管吸收之后转换成活性代谢物。


1.镇痛作用
(1)透明苯酚水及物在randall- selitto法(炎症足加压法)的试验中,ed50值为0.13mg/kg,相对于布洛芬、萘普待因、印度甲申,高出10 ~ 20倍的镇痛作用。
(2)老鼠发炎疼痛止痛法(lutto经口)中,异丙芬钠水和物的id50值为0.76mg/kg,具有和萘普待因、印度甲酸等相同的效力。
(3)慢性关节疼痛止痛法(lutto经口)中,roxsopfon钠水和物的ed50值为0.53mg/kg,具有最强的镇痛作用,同时还具有印度metsin、ketif芬、萘普待因生4 ~ 6倍的效力。这种药的镇痛作用是末梢性的。


2.抗炎症作用
对于克罗基丙酮显流酶(rate)、阿兹巴特关节炎等急速慢性炎症,它与布洛芬、萘普待因相似。


3.热解毒
丙酮丙芬钠对因酵母而产生的发热现象,与石墨烯、萘普待因其燃烧的过程几乎等比,同时还比印度甲申热3倍。


4.作用机制
本剂的作用机制是前列腺素合成抑制作用,它的作用在于胞嘧啶。ロキソプロフェンナトリウム水合物在口服时,胃粘膜刺激作用较弱的未变化身体消化管比此后迅速被吸收,抑制前列腺素生物合成作用的强烈活性代谢物trans-oh身体(srs)配位被转换成作用。

 

 


适应症
1.下列疾病及症状的消炎·镇痛
关节囊性关节炎、变形性关节炎、腰痛、肩关节周围炎、颈肩腕症候群、牙痛2.手术后外伤及拔牙后的镇痛·消炎
3.下列疾病的清热镇痛
急性上呼吸道炎(包括急性支气管炎和急性上呼吸道炎)

 

 


用法与用量
1.下列疾病及症状的消炎·镇痛
关节囊性关节炎、变形性关节炎、腰痛、肩关节周围炎、颈肩腕症候群、牙痛
通常成年人每天服用60毫克钙(无水化合物),每天服用3次。进行整顿的情况下,一次需要花费60 ~ 120mg。另外,根据年龄、症状适当增减。另外,应避免在肚子饿时服用药物。
2.手术后外伤及拔牙后的镇痛·消炎
通常成年人每天服用60毫克钙(无水化合物),每天服用3次。进行整顿的情况下,一次需要花费60 ~ 120mg。另外,根据年龄、症状适当增减。如果你饿了,最好不要服用药物
3.下列疾病的清热镇痛
急性上呼吸道炎(包括急性支气管炎和急性上呼吸道炎)
通常情况下,成人食用1次60mg。另外,根据年龄、症状适当增减。但原则上一天进行两次,一天最大限度为180mg。另外,应避免在肚子饿时服用药物。

 

 


制造销售元
第一三共制药

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