ASACOL tablets 400mg100c 溃疡性结肠炎治疗剂 美沙拉秦片 [0114987103012143]

ASACOL tablets 400mg100c 溃疡性结肠炎治疗剂 美沙拉秦片 [0114987103012143]

Price: US$117.10(tax included)

List Price: US$140.50

Weight: 20g

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Item description

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
ASACOL tablets 400mg
 Active ingredient:
Mesalazine
 Dosage form:
reddish brown to brown tablet, major axis: 14.7 mm, minor axis: 5.9 mm, thickness: 6.5 mm
 Print on wrapping:
アサコール錠400mg, ZP65

Effects of this medicine

This medicine releases its active ingredient in the large intestine. It eliminates activated oxygen released from inflammatory cells and inhibits the synthesis of leukotriene B4. It suppresses inflammation in the large intestine, and consequently improves abdominal pain and hematochezia. 
It is usually used in the treatment of ulcerative colitis.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines. 
    If you have: renal or hepatic disorder.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 2 tablets (800 mg of the active ingredient) at a time, 3 times daily, after meal. In remission stage of the disease, however, you may be instructed to take six tablets (2,400 mg of the active ingredient) at a time, once daily, as necessary. In active stage of the disease, take 3 tablets (1,200 mg of the active ingredient) at a time, 3 times daily, after meal. The dosage may be decreased according to the patient's condition. Strictly follow the instructions.
  • Swallow the tablet without chewing because the medicine is designed to dissolve and release the active ingredient in the large intestine.
  • If you miss a dose, take a dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should not take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Sometimes you will find broken pieces of the tablet (brown) in your stool, however, it is the coating agent and has no problem.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include abdominal pain, diarrhea, abdominal bloating, nausea, headache, exacerbation of ulcerative colitis, colonic polyp, liver function abnormality (including liver disorder) and fever. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • anemia, fever, throat pain, nasal bleeding, gum bleeding [myelosuppression, aplastic anemia, pancytopenia, agranulocytosis, leukopenia, neutropenia, thrombocytopenia]
  • chest pain, palpitation, shortness of breath, fever [myocarditis, pericarditis, pleurisy]
  • breathing difficulty, chest pain, dry cough [interstitial lung disease]
  • severe pain in the upper abdomen or lower back, fever, nausea [pancreatitis]
  • decreased urine output, edema, general malaise [interstitial nephritis, nephrotic syndrome, renal failure]
  • loss of appetite, general malaise, yellowing in the skin or conjunctiva ocular [hepatitis, liver dysfunction, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep the medicine out of the reach of children. Store it away from direct sunlight, heat and moisture.
  • Do not store the remainder and discard it.

简介:

英文名:Mesalazine
商品名:ASACOL
中文名:美沙拉嗪片


生产商:协和麒麟
アサコール錠400mg


药用分类名称
溃疡性结肠炎治疗剂


批准日期:2009年12月
商標名
ASACOL tablets 400mg

 

 

药效药理
实验性结肠炎模型的影响
在3%脱氧钠诱导的结肠炎模型中,口服甲酰胺100mg/kg,改善血液凳子,增加红细胞计数和血球蛋白值,白细胞计数减少。
作用机制
体外,过氧化氢清除作用,单氧清除作用,1,1-二苯基-2-丙烯酰基还原能力,脂质过氧化抑制作用和白细胞二烯B4生产抑制作用。

 


适应症
溃疡性结肠炎(严重除外)

 


用法与用量
通常,成人每天口服2,400mg,但餐后口服三次,在缓解期间,如有必要,每天2,400mg饭后口服给药。 在活动期间,每天口服3,600mg,分为三次。
另外,根据患者的状态适当减肥。

 


制造商
Zeria Shinyaku Co.Ltd.

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