LUMIGAN OPHTHALMIC SOLUTION 0.03% 贝美前列素滴眼液 [0114987123151174]

LUMIGAN OPHTHALMIC SOLUTION 0.03% 贝美前列素滴眼液 [0114987123151174]

Price: US$157.10(tax included)

List Price: US$188.50

Weight: 60g

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Item description

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
LUMIGAN OPHTHALMIC SOLUTION 0.03%
 Active ingredient:
Bimatoprost
 Dosage form:
clear and colorless ophthalmic solution
 Print on wrapping:
 

Effects of this medicine

This medicine acts on prostamide receptors to stimulate excretion of fluid (aqueous humors) in the eye via uveal outflow tract, and consequently lowers intraocular pressure.
It is usually used in the treatment of glaucoma and ocular hypertension.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: an eye with aphakia or intraocular lens, intraocular inflammation (iritis or uveitis), possible herpesvirus.
    If you wear contact lenses.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, apply 1 drop at a time, once daily. Strictly follow the instructions.
    Do not apply more than once daily since the effect of the medicine to lower intraocular pressure may be diminished if you apply the medicine frequently.
  • Before using, wash your hands with soap and water. Apply the medicine not to touch the tip of eye dropper to any surface of your eye. After instilling, close your eyes and do not blink for a while. The medicine attached around the eye after applying, wipe it off immediately with wet gauze or tissue, or wash the face with the eyes closed. If any leaked and attached medicine remains on the face, it may cause darkening around the eye, or lengthening and thickening of eyelashes. If you need to use other eyedrops, wait at least 5 minutes before applying the other eyedrop.
  • Contact lenses may be discolored due to the medicine. Therefore, you are wearing contact lenses, remove the contact lenses before applying the medicine, and wait for at least 15 minutes to wear the contact lenses.
  • If you miss a dose before the end of the day, apply 1 drop immediately. If you noticed it on the next day, do not apply the previous day's dose, and apply 1 drop once a day. You should not use either two drops at one time or twice a day.
  • If you accidentally use more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop using this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Blurred vision may occur temporarily after applying the medicine. Avoid driving a car or operating dangerous machinery until recovering from the symptom.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include conjunctival congestion, itching sensation in the eye, eyelid pigmentation, corneal erosion (foreign-body sensation, eye pain, sensitive to light, teary eye), abnormality in eyelashes (lengthening, thickening, darkening of eyelashes) and hypertrichosis in eyelid. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • eye (iris) color turns dark  [iris pigmentation]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • 2.5 mL of the solution is dispensed in a 5-mL container originally.
  • Keep out of the reach of children. Store at room temperature (1 to 30℃), away from direct sunlight.
  • Discard the remainder. Do not store them.
  • To avoid improper use and quality loss, do not transfer this solution to any other bottle or container.
  • Do not use any other solution in this bottle.

简介:

通用名称:贝美前列素滴眼液
商品名称:卢美根
英文名:Bimatoprost Ophthalmic Solution
 
 
适应症
主要用于降低对其他降眼压制剂不能耐受或不够敏感的(多次用药无法达到目标眼内压值)的开角型青光眼及高眼压症患者的眼内压。
 
 
用法用量
推荐剂量为每日一次,每晚滴一滴于患眼。每日使用本品次数不得超过一次,因为有资料表明频繁使用本品可导致其眼压效果减弱。
首次滴用本品约4小时后眼压开始降低,约于8-12小时之内作用达到最大。
本品可以与其它滴眼剂同时使用以降低眼压。如果同时使用多种治疗药物,则每两种药物的使用应当至少间隔五分钟。
 
 
禁忌
本品禁用于对贝美前列素或本品中其它任何成份过敏者。
 
 
警告
有报道本品会引起色素组织的变化。包括色素增加,睫毛增生和虹膜及眶周围组织(眼睑)的色素增加。这些变化可能是永久性的。卢美根可逐渐改变眼睛的颜色,通过增加黑色素细胞中的黑素体(色素颗粒)数目使虹膜中的褐色素增加。本品对色素细胞的长期影响以及对黑色素细胞的潜在损伤和/或色素颗粒在眼睛其他部位的沉积情况目前还不清楚。
 
 
注意事项
一般情况:有报道患者因使用多剂量包装的滴眼液而致细菌性角膜炎。大多数情况下,包装容器是由于患者同时患有角膜疾病或眼睛上皮表面破裂而被污染的(参加患者须知)。
患者虹膜褐色素沉着的变化是逐渐发生的,可能在数年内也不会有明显变化。通常,褐色素沉着以瞳孔为中心向周边进行扩散,但是整个虹膜或部分的褐色素也会更深。也该经常检查患者眼睛的颜色变化,以便提供更多有关色素沉着的资讯,并且依据临床情况,如果色素沉着继续则应停止用药。停止用药后虹膜的褐色素不会再增加,但已改变的颜色可能是永久性的。虹膜上的痣和斑点不受治疗的影响。患有活动性内眼炎症(如葡萄膜炎)的患者须谨慎用本品。
曾有报道,有患者使用本品后出现了黄斑水肿包括囊样黄斑水肿。无晶体患者、晶状体后囊撕裂的假性无晶体患者或已知有黄斑水肿危险的患者应谨慎用本品。
本品治疗闭角型、炎性及出血性青光眼尚无评价。
配戴有隐形眼镜时不应使用本品。
 
 
患者须知:患者应被告知,部分患者使用此药会出现睫毛变长、颜色变深、眼部皮肤颜色加深的现象,此现象可能是永久性的。
只需要治疗单侧眼睛的患者应该被告知出现两眼间睫毛长度,颜色或粗细不同和两眼的眼睑皮肤及虹膜颜色不同的可能。
患者应该被告知勿将药瓶的瓶口直接接触眼睛、眼周组织、手指以及其它物体的表面、以免药液被可致眼睛感染的细菌污染。使用被污染的药液会严重损伤眼睛进而使视力下降。
患者应该被告知在使用过程中,若眼部出现任何状况(如外伤或感染)或进行眼科手术,应立即资讯医生是否可以继续使用此多剂量包装的滴眼液。
患者应该告知在在使用过程中,若眼部出现反应,特别是结膜炎和眼睑反应时应及时咨询医生。
使用本品前应当摘下隐形眼镜,并在滴药15分钟后再配戴。应告诉患者本品中含有苯扎氯铵会被软性隐形眼镜吸收。
如果同时还使用其它药物,每两种药物的使用至少间隔5分钟。
 
 
孕妇及哺乳期妇女用药
孕妇:对妊娠期的妇女使用本品还缺少足够有良好对照的研究。因为动物的生殖试验还不能直接遇见人类反应,仅仅当作使用本品的益处远远大于其带给胎儿的危险性时,方可给孕妇使用。
哺乳期妇女:虽然动物试验表明动物的乳汁中分泌有贝美前列腺素,但本品是否会从人类乳汁中分泌还不清楚。由于许多药物都会分泌乳汁中,因此给哺乳期妇女使用本品应当谨慎。
儿童用药
儿童患者使用本品的安全性和有效性尚未确立。
老年患者用药
使用本品的安全性和有效性在老年人和成年人之间没有明显的临床差异。
 
 
药物相互作用
本品可以与其它滴眼剂同时使用以降低眼内压。如果同时使用多种治疗药物,则每两种药物的使用应当至少间隔五分钟。
 
 
药物过量
没有关于人体使用本品过量的的资料报导。如果过量使用本品,应该根据出现的症状进行相应处理。
 
 
贮藏
保持包装完整,储存于2-25C
 
 
製造販売元 
千寿製薬株式会社

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