MERCAZOLE Tablet 5mg100c 甲亢治疗剂 甲硫咪唑 [0114987123158838]

MERCAZOLE Tablet 5mg100c 甲亢治疗剂 甲硫咪唑 [0114987123158838]

Price: US$17.00(tax included)

List Price: US$20.40

Weight: 60g

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Item description

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
MERCAZOLE Tablet 5mg
 Active ingredient:
Thiamazole
 Dosage form:
pale yellow tablet (diameter: approx. 7.2mm, thickness: approx. 3.2mm)
 Print on wrapping:
(face) メルカゾール錠5mg, メルカゾール, 5mg, 甲状腺のお薬です
(back) MERCAZOLE TABLETS 5mg, メルカゾール, 5mg, 発熱, のどの痛み, 全身のだるさ等があらわれた際は, すぐに主治医へ連絡してください。

Effects of this medicine

This medicine works on thyroid gland to block the activity of enzyme which is necessary for thyroid hormone synthesis, consequently to suppress excess secretion of thyroid hormone. 
It is usually used to treat hyperthyroidism.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reaction (itch, rash etc.) to any medicines.
    If you have: hepatic disorder, leukopenia, or other blood disease.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For adults: In general, take the initial dosage of 6 tablets (30 mg of the active ingredient) in 3 to 4 divided doses a day. To treat severe hyperthyroidism, take 8 to 12 tablets (40 to 60 mg of the active ingredient) a day. When hyperthyroid symptoms almost disappear, the dosage will be tapered every 1 to 4 week(s). The maintenance dosage is 1 to 2 tablet(s) (5 to 10 mg of the active ingredient) in 1 to 2 divided doses a day.
    For children: In general, for children aged 5...initial dosage of 2 to 4 tablets (10 to 20 mg of the active ingredient) in 2 to 4 divided doses a day. For children aged 10 or over but under 15, take the initial dosage of 4 to 6 tablets (20 to 30 mg of the active ingredient) in 2 to 4 divided doses a day. When hyperthyroid symptoms almost disappear, the dosage will be tapered every 1 to 4 week(s). The maintenance dosage is 1 to 2 tablet(s) (5 to 10 mg of the active ingredient) in 1 to 2 divided doses a day. 
    For pregnant women: In general, take the initial dosage of 3 to 6 tablets (15 to 30 mg of the active ingredient) in 3 to 4 divided doses a day. When hyperthyroid symptoms almost disappear, the dosage will be tapered every 1 to 4 week(s). The maintenance dosage is 1 to 2 tablet(s) (5 to 10 mg of the active ingredient) in 1 to 2 divided doses a day. In order not to let your thyroid function level get lower than that during normal pregnancy, you should undergo the test every 2 weeks and take the least amount of the medicine possible.
    The dosage should be adjusted according to your age and symptoms in any case. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so. The medicine takes time to work. Discontinuing it half way will lead to an aggravated condition or recurrence of the disease. Neither stop taking the medicine nor increase the dosage on your own. And keep taking it according to the instructions of your doctor.

Precautions while taking this medicine

  • Your doctor will examine your thyroid gland condition and decide the appropriate dosage for you based on the result from it. Also you will be examined periodically to detect its adverse reactions in early stages. Do not forget to see your doctor and undergo the test.
  • It has been reported that some patients had serious agranulocytosis mainly within 2 months after starting the medication and died of it. If you have agranulocytosis, you will be easily infected and have "fever", "sore throat" and "general lassitude" which are the same symptoms as when you have a cold or adenoiditis. If you notice that you are having any of these symptoms mentioned above, go to see your doctor immediately. Do not ignore it.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, hives and fever. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • fever, lassitude, sore throat [pancytopenia, aplastic anemia, agranulocytosis, leukopenia]
  • nose/gum bleeding, bruise due to subcutaneous bleeding [hypoprothrombinemia, factor VII deficiency, thrombocytopenia, thrombocytopenic purpura]
  • lassitude, loss of appetite, yellowness in the skin and/or the white of the eye [hepatic function disorder, jaundice]
  • joint pain/enlargement, fever [polyarthritis]
  • fever, butterfly-like red punctum on the face, muscle pain [SLE - like symptom]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from heat, moisture and light.
  • Discard the remainder. Do not store them. Ask the pharmacist or healthcare facility how to discard them.

成分与分量

MERCAZOLE


 

剂型或形状

片剂

 

功效

作用于甲状腺,抑制合成甲状腺激素所必需的酶的功能,并抑制甲状腺激素的过度分泌。
通常用于治疗甲状腺功能亢进。



用法用量

成人:成人每天服用6片(30毫克),分3〜4次服用。重症患者,每天服用8至12片(40至60毫克),分3〜4次服用。
如果功能亢进症状几乎消失,每4周为一个周期逐渐减少用量,减到维持量每日1至2次,每日总用量1至2片(5至10mg)。
儿童:5至10岁未满的儿童,初始剂量为2至4片(10至20毫克为主要成分),10岁以上-15岁未满4至6片(20至30毫克),分2〜4次服用。
如果功能亢进症状几乎消失,每4周为一个周期逐渐减少用量,减到维持量每日服用1至2次,每日总用量1至2片(5至10mg)。
孕妇:孕妇每天服用3〜6粒(15〜30毫克为主要成分),分3〜4次服用。
如果功能亢进症状几乎消失,每4周为一个周期逐渐减少用量,减到维持量每日服用1至2次,每日总用量1至2片(5至10mg)。
为了防止正常怀孕期间的甲状腺功能测试值降低,每2周检查一次,并采取必要的最小量。
根据年龄和症状,可增加或减少用量。请务必遵照医生指示。


 

 



副作用

皮疹,荨麻疹,发烧等。 如果您注意到这种症状,请咨询您的医生或药剂师。

 

 

使用上请注意

医生检查甲状腺的状况,并根据结果决定用量。 定期检测以尽早发现副作用。 请不要忘记定期检查。
曾报道死亡病例,副作用导致严重的粒细胞缺乏症,主要发生在服用该药后2个月内。 当发生粒细胞缺乏症时,容易感染,“发烧”,“喉咙痛”,“全身不适(疲劳)”等似乎与感冒和扁桃体炎相似。 如果您注意到这些症状,请不要将其看作感冒,并尽快去医院看诊。

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